U1 Small Nuclear Ribonucleoprotein

A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.

Also Known As:

Ribonucleoprotein, U1 Small Nuclear; Ribonucleoproteins, Small, U1; Small Nuclear Ribonucleoproteins, U1; U1 Small Nuclear Ribonucleoproteins; U1 snRNP

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Carrier Proteins: 13306
    - RNA-Binding Proteins: 3439
      - Ribonucleoproteins: 1314
        Small Nuclear Ribonucleoproteins: 271
        U1 Small Nuclear Ribonucleoprotein: 65
      - RNA Splicing Factors: 1109
        U1 Small Nuclear Ribonucleoprotein: 65
  - Nucleoproteins: 1892
    - RNA-Binding Proteins: 3439
      - Ribonucleoproteins: 1314
        Small Nuclear Ribonucleoproteins: 271
        U1 Small Nuclear Ribonucleoprotein: 65
      - RNA Splicing Factors: 1109
        U1 Small Nuclear Ribonucleoprotein: 65

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Disease

Drug/Important Bio-Agent (IBA)